70% of the body’s immune cells are found in the gastrointestinal tract.
Multiple studies have shown that improving gut health is one of the most effective ways to support a strong immune system. That’s why Probi created Probi Defendum®, a probiotic immune concept based on a combination of the Lactiplantibacillus plantarum HEAL9 (HEAL9™) and Lacticaseibacillus paracasei 8700:2 strains.
Probi Defendum® has proven efficacy and safety in clinical studies involving over 1700 individuals, primarily targeting respiratory health in both adults and children.
Probiotics for preventing acute upper respiratory tract infections
Authors: Zhao, Y., Dong, B.R., Hao, Q.
Publication: Cochrane Database of Systematic Reviews 2022, Issue 8. Art. No.: CD006895.
https://pubmed.ncbi.nlm.nih.gov/36001877/
Probiotic use in the prophylaxis of periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome: a retrospective cohort study
Authors: Batu, E.D., Akca, U.K., Basaran, O., Bilginer, Y., Özen, S.
Publication: Rheumatology International, 42, 1207- 1211
https://pubmed.ncbi.nlm.nih.gov/34994815/
Randomised, double-blind and placebo-controlled study using new probiotic lactobacilli for strengthening the body immune defence against viral infections
Authors: Berggren A, Lazou Ahrén I, Larsson N, Önning G
Publication: Eur J Nutr. 2011;50(3):203-10.
https://link.springer.com/article/10.1007/s00394-010-0127-6
Randomized, double-blind and placebo-controlled study using a combination of two probiotic lactobacilli to alleviate symptoms and frequency of common cold
Authors: Busch R, Gruenwald J, Dudek S
Publication: Food Nutr Sci. 2013;4:13-20.
https://www.scirp.org/index
Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomized, double-blind, placebo-controlled clinical study
Authors: Lazou Ahrén I, Berggren A, Teixeira C, Martinsson Niskanen T, Larsson N.
Publication: Eur J Nutr. 2020 Feb;59(1):409-417.
https://link.springer.com/article/10.1007/s00394-019-02137-8
Probiotics for preventing acute upper respiratory tract infections
Authors: Zhao, Y., Dong, B.R., Hao, Q.
Publication: Cochrane Database of Systematic Reviews 2022, Issue 8. Art. No.: CD006895.
https://pubmed.ncbi.nlm.nih.gov/36001877/
Probiotic use in the prophylaxis of periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome: a retrospective cohort study
Authors: Batu, E.D., Akca, U.K., Basaran, O., Bilginer, Y., Özen, S.
Publication: Rheumatology International, 42, 1207- 1211
https://pubmed.ncbi.nlm.nih.gov/34994815/
Randomised, double-blind and placebo-controlled study using new probiotic lactobacilli for strengthening the body immune defence against viral infections
Authors: Berggren A, Lazou Ahrén I, Larsson N, Önning G
Publication: Eur J Nutr. 2011;50(3):203-10.
https://link.springer.com/article/10.1007/s00394-010-0127-6
Randomized, double-blind and placebo-controlled study using a combination of two probiotic lactobacilli to alleviate symptoms and frequency of common cold
Authors: Busch R, Gruenwald J, Dudek S
Publication: Food Nutr Sci. 2013;4:13-20.
https://www.scirp.org/index
Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomized, double-blind, placebo-controlled clinical study
Authors: Lazou Ahrén I, Berggren A, Teixeira C, Martinsson Niskanen T, Larsson N.
Publication: Eur J Nutr. 2020 Feb;59(1):409-417.
https://link.springer.com/article/10.1007/s00394-019-02137-8
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