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Probiotic Support for Strong Bones

Probi Osteo®

Strong bones for an active life.

In most people under the age of 30, the continuous formation and breakdown of bone tissue (remodeling) follows a predictable, balanced pattern. However, after the age of 30, this balance is disrupted. Bone loss exceeds formation, resulting in a gradual loss of bone density.

Probi® Osteo is a probiotic bone health concept based on the combination of Lactiplantibacillus plantarum HEAL9 (HEAL9™), Lactiplantibacillus plantarum HEAL19, and Lacticaseibacillus paracasei 8700:2, which is clinically documented to support bone health.

Key Facts
*These statements have not been evaluated by the US Food & Drug Administration or the European Food and Safety Authority. This product is not intended to diagnose, treat, cure, or prevent any disease.

Probiotics Inhibit Cartilage Damage and Progression of Osteoarthritis in Mice
Authors: Sophocleous, A., Azfer, A., Huesa, C., Stylianou, E., & Ralston, S. H.
Publication: Calcified tissue international, 112(1), 66–73.
https://pubmed.ncbi.nlm.nih.gov/36261653/

A probiotic mix partially protects against castration-induced bone loss in male mice
Authors: Lina Lawenius, Hannah Colldén, Karin L Gustafsson, Jianyao Wu, Louise Grahnemo, Liesbeth Vandenput, Claes Ohlsson, Klara Sjögren
Publication: J Endocrinol 2022;254(2):91-101.
https://pubmed.ncbi.nlm.nih.gov/35661635/

Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in mice
Authors: Claes Ohlsson, Lina Lawenius, Annica Andersson, Karin Gustafsson, Jianyao Wu, Marie Lagerquist, Sofia Movérare-Skrtic, Ulrika Islander, Klara Sjögren
Publication: Am J Physiol Endocrinol Metab. 2021;320(3):E591-E597
https://pubmed.ncbi.nlm.nih.gov/33522399/

Probiotic treatment using a mix of three Lactobacillus strains for lumbar spine bone loss in postmenopausal women: a randomised, double-blind, placebo-controlled, multicentre trial
Authors: Jansson P-A, Curiac D, Lazou Ahrén I, Hansson F, Martinsson Niskanen T, Sjögren K, Ohlsson C
Publication: The Lancet Rheumatology 2019;1(3):e154-e162.
https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(19)30068-2/abstract

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*These statements have not been evaluated by the US Food & Drug Administration or the European Food and Safety Authority. This product is not intended to diagnose, treat, cure, or prevent any disease.

Probiotics Inhibit Cartilage Damage and Progression of Osteoarthritis in Mice
Authors: Sophocleous, A., Azfer, A., Huesa, C., Stylianou, E., & Ralston, S. H.
Publication: Calcified tissue international, 112(1), 66–73.
https://pubmed.ncbi.nlm.nih.gov/36261653/

A probiotic mix partially protects against castration-induced bone loss in male mice
Authors: Lina Lawenius, Hannah Colldén, Karin L Gustafsson, Jianyao Wu, Louise Grahnemo, Liesbeth Vandenput, Claes Ohlsson, Klara Sjögren
Publication: J Endocrinol 2022;254(2):91-101.
https://pubmed.ncbi.nlm.nih.gov/35661635/

Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in mice
Authors: Claes Ohlsson, Lina Lawenius, Annica Andersson, Karin Gustafsson, Jianyao Wu, Marie Lagerquist, Sofia Movérare-Skrtic, Ulrika Islander, Klara Sjögren
Publication: Am J Physiol Endocrinol Metab. 2021;320(3):E591-E597
https://pubmed.ncbi.nlm.nih.gov/33522399/

Probiotic treatment using a mix of three Lactobacillus strains for lumbar spine bone loss in postmenopausal women: a randomised, double-blind, placebo-controlled, multicentre trial
Authors: Jansson P-A, Curiac D, Lazou Ahrén I, Hansson F, Martinsson Niskanen T, Sjögren K, Ohlsson C
Publication: The Lancet Rheumatology 2019;1(3):e154-e162.
https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(19)30068-2/abstract

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Health Indications

Applications

Probi Osteo® is ideal for capsules and stick-packs, as well as for functional foods such as beverages and powder products.
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